The Cheapest GLP-1 in 2026: Real Prices, Ranked
Every price below is a provider’s real published rate, with its honest condition - promo pricing, prepaid plans, first-month rates - printed right under the number. Sorted cheapest first.
Last updated: Aug 16, 2026
We may earn a commission when you visit providers through links on this page - it never affects our rankings (how we stay objective). This content is for information only and is not medical advice - always consult a licensed clinician before starting treatment.
The short answer
The cheapest GLP-1 we track is wellmedr - compounded semaglutide at $59/month on a 12-month plan, and the cheapest tirzepatide at $99/month. If you don’t want a commitment, embody is the cheapest month-to-month at $69/$119 with 1-2 day shipping. For one flat price covering either medication - as injections or needle-free drops - DirectMeds charges $147/month at every dose. Brand-name Ozempic and Zepbound list at $1,149-$1,599/month by comparison.
The 2026 GLP-1 price index
Eight providers, ranked by their published semaglutide price. Trustpilot records shown are real; where a provider has no published rating, we say so instead of inventing one.
Lowest ongoing price on the market - same price at every dose
Ships in 3-5 business days · Trustpilot 4.7 across 1,205 reviews
Semaglutide
12-month plan; locked for life
Tirzepatide
shipped every 4 weeks
Cheapest with no commitment - month to month, ships in 1-2 days
Ships in 1-2 days, cold-chain · Trustpilot 3.8 across 4,956 reviews
Semaglutide
reg. $79; month-to-month
Tirzepatide
reg. $129; month-to-month
Flat pricing at every dose, plus a real brand-name shelf
Free shipping in 5-7 days · No published Trustpilot rating
Semaglutide
reg. $199; flat at every dose
Tirzepatide
reg. $299; flat at every dose
All-in prepaid year with overnight cold-chain delivery
Overnight cold-chain shipping · No published Trustpilot rating
Semaglutide
12-mo prepaid - $1,188 at checkout
Tirzepatide
per month
One flat price for both medications - injections or drops
Free 1-2 day shipping · Trustpilot 4.6 across 13,901 reviews
Semaglutide
flat at every dose
Tirzepatide
flat at every dose
All-inclusive care: visits, dietician and coaching in the price
Free shipping · Trustpilot 4.4 across 14,372 reviews
Semaglutide
all-inclusive; tablets $249
Tirzepatide
not offered
Custom dosing with unlimited provider check-ins
Free tracked delivery, often next-day · Trustpilot 3.6 across 5,497 reviews
Semaglutide
first month; reg. $299
Tirzepatide
per month
Coaching included and a 5%-in-120-days money-back guarantee
Home delivery included · Trustpilot 4.7 across 1,120 reviews
Semaglutide
20% off month one
Tirzepatide
20% off month one
What a year of semaglutide actually costs
Headline prices hide the arithmetic - first-month promos expire and prepaid plans front-load the cost. This is the real 12-month math per provider, promo conditions applied exactly as published, next to the cheapest brand-name year (Ozempic at altRx’s $1,149/month = $13,788).
| Provider | The 12-month math | First-year total | Saved vs brand Ozempic |
|---|---|---|---|
| wellmedr | $59 x 12 (12-month plan rate) | $708 | $13,080 |
| embody | $69 x 12 (promo; $948 at the $79 regular rate) | $828 | $12,960 |
| altRx | $89 x 12, flat at every dose | $1,068 | $12,720 |
| HealthRx | $1,188 prepaid at checkout ($99/mo effective) | $1,188 | $12,600 |
| DirectMeds | $147 x 12, flat at every dose | $1,764 | $12,024 |
| Medvi | $179 x 12, all-inclusive with coaching | $2,148 | $11,640 |
| SHED | $159 first month (20% off) + $199 x 11 | $2,348 | $11,440 |
| trimrx | $179 first month + $299 x 11 regular | $3,468 | $10,320 |
Assumes published prices hold for 12 months and promo conditions apply exactly as listed (trimrx’s $179 and SHED’s 20% off are month-one rates; embody’s $69 is promotional against $79 regular). Savings compare against Ozempic’s lowest listed brand price on our providers’ shelves ($1,149/month at altRx; wellmedr lists it at $1,399). What’s bundled differs - Medvi and SHED include coaching layers others don’t - so the cheapest row isn’t automatically the best fit.
Semaglutide vs tirzepatide: what the price difference buys
Tirzepatide costs $40-$110/month more at most providers. Whether it’s worth it is a clinical question - here’s the published evidence side by side.
| Semaglutide | Tirzepatide | |
|---|---|---|
| Mechanism | GLP-1 receptor agonist | Dual GIP + GLP-1 receptor agonist |
| Brand names | Ozempic, Wegovy (injection); Rybelsus (oral) | Mounjaro, Zepbound |
| Pivotal trial result | ~15% average body-weight loss at 68 weeks (STEP 1, 2.4 mg) | ~21% average body-weight loss at 72 weeks (SURMOUNT-1, 15 mg) |
| Dosing | One injection per week | One injection per week |
| Cheapest compounded price | $59/mo (wellmedr, 12-month plan) | $99/mo (wellmedr) |
| Cheapest month-to-month | $69/mo (embody) | $119/mo (embody) |
| Same price for both | $147/mo flat (DirectMeds - injections or drops) | $147/mo flat (DirectMeds) |
Trial figures are from the published STEP 1 (NEJM, 2021) and SURMOUNT-1 (NEJM, 2022) studies, cited in the sources below; results are trial averages at the highest studied doses, not guarantees. Which medication is appropriate for you is your prescribing clinician’s decision.
Already on Ozempic, Wegovy or Zepbound?
If you’re paying brand prices today, switching to the compounded version of the same active ingredient is usually a $1,000+/month difference. We wrote a dedicated guide to how the switch actually works - and what to check first.
Cheapest GLP-1: FAQs
What is the cheapest GLP-1 medication in 2026?
The cheapest GLP-1 program among the providers we track is wellmedr, at $59/month for compounded semaglutide on a 12-month plan - the same price at every dose. The cheapest with no commitment is embody at $69/month, month to month. All prices on this page are the providers' real published rates, with their conditions disclosed.
What is the cheapest tirzepatide?
wellmedr lists compounded tirzepatide from $99/month, the lowest published tirzepatide price we track. embody is the cheapest month-to-month option at $119/month ($129 regular), and DirectMeds charges a flat $147/month for either medication - including a needle-free sublingual drops format at the same price.
Why are these so much cheaper than Ozempic?
Brand-name Ozempic, Wegovy and Zepbound list for roughly $1,149-$1,599/month on our providers' own brand shelves. The programs on this page prescribe compounded semaglutide or tirzepatide instead - the same active ingredients, prepared by state-licensed compounding pharmacies and sold cash-pay at a flat monthly rate. Compounded medications are not FDA-approved brand drugs, which is why the provider's pharmacy standards (LegitScript certification, licensed 503A pharmacies) matter more than the price alone.
Do I need insurance for any of these?
No - every program on this page is cash-pay, with the consultation and prescription included in the monthly price. No insurance and no prior authorization is required. Several (Medvi, SHED) are HSA/FSA approved, so you can pay with pre-tax health funds.
What's the catch with the lowest prices?
Commitment and speed. The $59/month headline at wellmedr is tied to a 12-month plan, and HealthRx's $99/month is a 12-month prepaid plan with $1,188 due at checkout. Month-to-month flexibility costs slightly more (embody at $69/$119). Slower shipping is the other trade: altRx at $89 ships in about 5-7 days versus 1-2 days at embody and DirectMeds. Every condition is listed under each price above - there are no unlisted catches we're aware of.
Are cheap compounded GLP-1s safe?
Price doesn't determine safety - the pharmacy and the clinical process do. Every provider in this index requires a medical intake reviewed by a licensed clinician, and the ones we rank highest work with state-licensed 503A compounding pharmacies (embody and HealthRx are LegitScript-certified). Compounded medications are not FDA-approved brand drugs, so avoid any site that skips the medical review or won't name its pharmacy standards. Always consult a licensed clinician about whether GLP-1 treatment is appropriate for you.
Keep comparing: Ozempic alternatives · pills vs injections · embody vs wellmedr · all reviews
Sources & medical references
Treatment facts on this page are grounded in regulatory guidance and peer-reviewed research. Pricing and plan details come from each provider's published information.
- 1.Once-Weekly Semaglutide in Adults with Overweight or Obesity (STEP 1 trial) - New England Journal of Medicine, 2021
- 2.Tirzepatide Once Weekly for the Treatment of Obesity (SURMOUNT-1 trial) - New England Journal of Medicine, 2022
- 3.FDA Approves New Drug Treatment for Chronic Weight Management (semaglutide / Wegovy) - U.S. Food & Drug Administration, 2021
- 4.FDA Approves New Medication for Chronic Weight Management (tirzepatide / Zepbound) - U.S. Food & Drug Administration, 2023
- 5.FDA's Concerns with Unapproved GLP-1 Drugs Used for Weight Loss - U.S. Food & Drug Administration
- 6.Human Drug Compounding (503A pharmacy standards) - U.S. Food & Drug Administration
- 7.Semaglutide Injection - drug information - MedlinePlus, U.S. National Library of Medicine (NIH)
Prices are the providers’ published cash-pay rates at the time of the last update and can change; confirm current pricing on the provider’s site. Compounded medications are not FDA-approved brand drugs. treatmentshub.com is not a medical provider - this page is for information only and is not medical advice.