Medvi vs TrimRx vs SHED: The Support-Tier Showdown
Last updated: Sep 1, 2026
Medical reviewer: Francheska Capistrano, RMT, MPH · Medical Content Reviewer
Reviews this site’s health content for scientific accuracy · Written by Treatments Hub Research Team · How we review
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Here’s the short version
These three sell more than medication - each wraps the same compounded GLP-1s in a different support philosophy, from Medvi's current $99 promo to SHED's $199. Medvi bundles video visits, a dietician and care coaching behind a 14,987-review Trustpilot record. TrimRx sells flexibility: no contract, optional discounts, clinical guidance. SHED sells accountability: formal health coaching plus the market's only lose-5%-in-120-days-or-your-money-back guarantee.
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Medvi vs TrimRx vs SHED: side by side
Real published prices and terms - the differences that actually decide this matchup.
| Medvi | TrimRx | SHED | |
|---|---|---|---|
| Semaglutide | $99/mo promo (reg. $199), all-inclusive | $149/mo, same at every dose | $199/mo (20% off first month) |
| Tirzepatide | $166/mo promo (reg. $299) | $259/mo | $299/mo (20% off first month) |
| Billing & commitment | Monthly, all-inclusive - no surprise charges; HSA/FSA approved | Monthly - no long-term contract; multi-month discounts | Monthly; HSA/FSA approved |
| Shipping | Free shipping | Free home delivery | Free home delivery |
| Support | Video visits + free dietician & care coaching | Licensed clinical guidance through dose changes | Provider visit + health coaching included |
| Guarantee / refund | - | - | Lose 5% of body weight in 120 days or your money back |
| Standout | 4.3 on Trustpilot across 14,987 reviews | Flexibility-first: month-to-month always available | The market's firmest results guarantee |
Our verdict
Match the model to your failure mode. If past attempts failed for lack of guidance, Medvi's high-touch care - with the receipts to prove it works - is the pick. If you want premium care without being locked to anything, TrimRx. If you need stakes and structure to follow through, SHED's guarantee literally pays you back if the program doesn't deliver. On current pricing Medvi's $99 promo is also the cheapest of the three - but the support philosophy, not the price, is the real choice.
Medvi vs TrimRx vs SHED: FAQs
Is Medvi, TrimRx or SHED better for support?
They support differently: Medvi includes video visits with providers plus a free dietician and care coaching (rated 4.3 across 14,987 Trustpilot reviews); SHED includes formal health coaching backed by a money-back guarantee; TrimRx includes clinical guidance through dose changes with a flexibility-first, no-contract model.
Which has a money-back guarantee?
SHED - lose 5% of your body weight in 120 days or your money back, conditioned on following the program (terms on its site). Medvi and TrimRx don't advertise results guarantees.
Are these worth it over cheaper GLP-1 providers?
The active ingredients are the same as the $49-$99 budget tier - the premium buys the support layer. If coaching, accountability or a personal provider relationship is what determines whether you stick with treatment, the tier can pay for itself; if you're self-directed, the budget tier delivers the same medication for less.
Break it down two at a time
The head-to-head comparisons between these providers.
Sources & medical references
Treatment facts on this page are grounded in regulatory guidance and peer-reviewed research. Pricing and plan details come from each provider's published information. This content is for information only and is not medical advice - always consult a licensed clinician before starting treatment.
- 1.Once-Weekly Semaglutide in Adults with Overweight or Obesity (STEP 1 trial) - New England Journal of Medicine, 2021
- 2.Tirzepatide Once Weekly for the Treatment of Obesity (SURMOUNT-1 trial) - New England Journal of Medicine, 2022
- 3.FDA Approves New Drug Treatment for Chronic Weight Management (semaglutide / Wegovy) - U.S. Food & Drug Administration, 2021
- 4.FDA Approves New Medication for Chronic Weight Management (tirzepatide / Zepbound) - U.S. Food & Drug Administration, 2023
- 5.FDA's Concerns with Unapproved GLP-1 Drugs Used for Weight Loss - U.S. Food & Drug Administration
- 6.Human Drug Compounding (503A pharmacy standards) - U.S. Food & Drug Administration
- 7.Semaglutide Injection - drug information - MedlinePlus, U.S. National Library of Medicine (NIH)