SHED bundles three things - medication, coaching, and a money-back guarantee - so every alternative unbundles something. The decision tree is short: if the coaching and accountability are why you're here, only two rivals keep meaningful support in the box. If you've realized you mainly need the medication, five providers sell it for $52-$140/month less. Decide which reader you are; the rest is just names and prices.
The fork: support or savings
Our top-rated GLP-1 providers
Our recommended telehealth providers - the same cards from our full comparison.
1
Exceptional
9.7out of 10
Most Comprehensive GLP-1 Medication Access
Transparent pricingNo insurance required
Treatments offered
Compounded semaglutide (GLP-1) injection · Compounded tirzepatide (GLP-1 + GIP) injection · Brand-name Zepbound and Wegovy · One simple injection per week
Starting price
$199$89/month
*Compounded medications are not FDA-approved.
- Compounded GLP-1 from $89/mo, GLP-1 + GIP from $149/mo
- Brand-name options too: Zepbound and Wegovy
- Clinician-guided - physician, PA, or nurse practitioner
- Free shipping (about 5-7 days)
Pricing starts at
from $89/month
altRx bills itself as "the #1 most affordable GLP-1 program," and its published prices largely back that up: compounded GLP-1 (semaglutide) from $89/month and GLP-1 + GIP (tirzepatide) from $149/month - flat at every dose, so the price doesn't climb as you titrate up - alongside one of the few genuine brand-name shelves in this space (Ozempic $1,149, Zepbound $1,249, Wegovy $1,579 per month). It's a self-pay telehealth service: you complete a short assessment, a licensed provider (physician, PA, or nurse practitioner) reviews it, and if appropriate a prescription goes to a licensed US pharmacy, with free shipping in about 5-7 days. No insurance is required, Buy Now, Pay Later is available, and you can pause or cancel anytime. Two things to know before the details: shipping is slower than the 1-2 day providers (embody, DirectMeds), and Trustpilot does not currently display an aggregate score on altRx's profile - the individual reviews we quote on this page are real, but there's no independent average to lean on the way there is for rivals like Medvi (4.3 across 14,836) or embody (3.8 across 8,398). One of the real 4-star reviews we surface notes a refill 'yet to be fulfilled with zero reason as to why' - worth factoring in alongside the price advantage.
Read full altRx review2
Excellent
9.6out of 10
Limited Offer - GLP-1 for $69/mon
Money-back guaranteeFree expedited delivery
Treatments offered
Compounded semaglutide injections (GLP-1) · Compounded tirzepatide injections (GLP-1 + GIP) · 100% online doctor review and prescription · Dosage adjustments through the patient portal
Starting price
$79$69/month
*Compounded medications are not FDA-approved.
- Compounded semaglutide ($69/mo) and tirzepatide ($119/mo)
- 5-minute health qualifier; doctor review usually within 24 hrs
- Free 1-2 day shipping - temperature-controlled, tracked, insured
- No insurance required, no clinic visits, cancel anytime
Pricing starts at
from $69/month
embody offers doctor-prescribed GLP-1 weight loss treatment - compounded semaglutide and tirzepatide injections - through a 100% online process. Getting started takes a roughly 5-minute health qualifier, after which a medical practitioner reviews your chart (embody says usually within 24 hours, often under 5). Pricing is flat and simple: $69/month for semaglutide and $119/month for tirzepatide, with no insurance required, no hidden fees, and no clinic visits. Medication ships in 1-2 days in temperature-controlled, tracked, insured packaging, and embody is LegitScript-certified and works with US-based 503A compounding pharmacies. On Trustpilot, embody averages 3.8 across 8,398 reviews - an honest, mixed-to-positive record whose recent reviews cluster around two themes: responsive, proactive customer service ('from my very first inquiry I've had excellent communication... customer service updated me every step,' writes one tirzepatide patient) and the no-surprises pricing ('Love the fact that there are no surprises as in costly up front cost'). A 3.7 also means a minority of customers had negative experiences - worth reading both ends of the reviews before deciding, as with any provider.
Read full embody review3
Excellent
9.4out of 10
Limited time offer - $140 off all weight loss plans
HIPAA compliantMade in USA
Treatments offered
Compounded semaglutide (GLP-1) injection · Compounded tirzepatide (GLP-1 + GIP) injection · Custom dosing schedules set by your provider · Unlimited check-ins throughout treatment
Starting price
$289$149/month
*Compounded medications are not FDA-approved.
- Compounded semaglutide $149/month - same price at every dose
- Compounded tirzepatide $259/month
- Custom dosing with unlimited provider check-ins
- Free consultation and free tracked delivery - often next-day
Pricing starts at
from $149/month
trimrx is a telehealth GLP-1 program built around custom dosing: compounded semaglutide at $149/month (a $140 discount applied, the same price at every dose) and compounded tirzepatide at $259/month, with the consultation, tracked delivery, and unlimited provider check-ins all included in the price. The flow is the standard cash-pay one - a free 2-minute assessment, review by a qualified doctor (with a telehealth call if more information is needed), then free tracked shipping that often arrives as soon as the next day. On Trustpilot, trimrx averages 3.7 across 5,670 reviews - a genuinely mixed record. The positive end is vivid: 'I have lost 41 lbs... My high blood pressure is gone,' writes one tirzepatide patient, and another praises a rep who was 'very kind and helpful' even as the reviewer ultimately chose their own doctor. But a 3.6 means a meaningful minority report problems, and it's the weakest published average among the affiliate providers in our ranking. Read both ends of its recent reviews before signing up - and weigh the price against the $49-$89 entry tier at wellmedr, embody and altRx.
Read full trimrx review
SHED reviews on
Trustpilot(1,134 reviews)
Sep 23, 2026
great customer service
“Gao helped me with several issues very quickly. Very personable too. And I love Shed too”
B
BAG
US
Sep 14, 2026
Continued to charge me for months after...
“Continued to charge me for months after I stopped the medication. Exclusively AI customer support so don't expect any help. I was told to not expect a refund so I am having to go through my credit card company. Extremely shady company. Edit: in response to their reply, I already contacted support and was told that they will not refund the $1200 they took and delivered nothing.”
J
Justin J.
US
Sep 15, 2026
Your communications are excellent
“Your communications are excellent! Ethan was quick to reply to my request for clarifications. Recommended!”
B
BB
US
Sep 15, 2026
Savannah - real person
“The app & chat function are a little clunky, but improving. Once you start emailing (not chatting) with a real person, Savannah was the best. Another agent told me I was SOL, but Savannah went a step further and resolved my issue.”
R
R M
US
Reviews are individual experiences quoted verbatim from public Trustpilot profiles, names shortened; any weight-loss result mentioned is one person's and is not typical - results vary. Trustpilot is a trademark of Trustpilot A/S and is not affiliated with this site.
Keep the support: Medvi, or wellmedr's lighter version
Medvi (currently $99/$166 promotional, all-inclusive, HSA/FSA) is the nearest substitute in spirit: no formal guarantee, but video visits, a dietician and care coaching, and the receipts SHED can't match - 4.3 on Trustpilot across 14,836 reviews praising exactly that support. At the promo rate you save $100/month and trade the guarantee for a track record. wellmedr ($49/$89) runs the budget version of the same idea: a Medical Weight-Care Coach on every plan plus its own weight-loss warranty - the only other results-linked promise in our ranking - at 30% of SHED's price, with a 12-month lock for the best rate.
Keep the cash: the medication-first tier
embody - $69 flat, no commitment, 1-2 day free shipping, refund if not approved: the cleanest exit if you want simplicity. HealthRx - $99/month on a 12-month prepaid plan ($1,188 upfront) with overnight cold-chain delivery. DirectMeds - flat $147 either medication, and the only needle-free drops in the group; its tirzepatide beats SHED's by $152/month. altRx - $89/$149 with the cheapest brand-name shelf (Ozempic $1,149) if that's where you're heading.
| Alternative | Semaglutide | Support kept | Annual saving vs SHED |
|---|---|---|---|
| Medvi | $99/mo promo | High (visits + dietician) | $1,200 |
| DirectMeds | $147/mo | Low | $624 |
| HealthRx | $99/mo* | Low-mid (check-ins) | $1,200 |
| altRx | $89/mo | Low | $1,320 |
| embody | $69/mo | Low-mid | $1,560 |
| wellmedr | $49/mo | Mid (coach + warranty) | $1,680 |
*prepaid annual.
Shop GLP-1 plans by product
Every provider's published plans - cheapest first, conditions under each price.
Guarantee vs warranty vs refund: read the small words
Three providers in this market attach promises to their programs, and they are not the same instrument. SHED's is a results guarantee: a defined outcome (5% of body weight), a defined window (120 days), money back if the program doesn't deliver - the strongest form, conditioned on following the program. wellmedr's weight-loss warranty is results-linked too but structured differently; its terms live on their site and deserve the same careful read. embody's promise is narrower and earlier: a full refund if a provider doesn't approve you - it protects the application, not the outcome. Rank them by where your anxiety actually lives: worried the medication won't work for you → SHED; worried about long-commitment pricing → wellmedr; worried you won't qualify at all → embody. Matching the promise to the fear is the whole game.
What To Know Before Starting GLP-1 Treatment
Before starting GLP-1 treatment, it's important to understand a few key things. These medications require a prescription from a licensed clinician and aren't suitable for everyone. Some people may experience side effects, especially during the first few weeks as the body adjusts.
GLP-1s also tend to work best when combined with basic lifestyle habits like balanced nutrition and regular physical activity.
That's why choosing a provider that offers proper medical screening and ongoing follow-up support is essential for both safety and long-term success.
The case for not leaving
One scenario argues for staying put: you're within reach of the 120-day guarantee window and following the program. Walking away from a live money-back position to save monthly cost is backwards - see the commitment through, bank the result (or the refund), then downshift to a cheaper maintenance provider once the guarantee has done its job. Providers are easy to switch; a guarantee period isn't recoverable.
→ Not sure which reader you are? The quiz sorts it in a minute
This article is general information, not medical advice. Prices as listed at the time of writing.