Weight Loss Medication Cost Guide (2026): Complete Pricing Breakdown

At retail price, brand-name GLP-1 medications are expensive. Wegovy (semaglutide for weight loss) typically costs between $1,300 and $1,400 per month. Ozempic runs around $900 to $1,000 per month.

Zepbound (tirzepatide for weight loss) is priced similarly to Wegovy at roughly $1,000 to $1,100 per month. Mounjaro (tirzepatide for diabetes) falls in a similar range.

These prices are without insurance or manufacturer discounts, which can significantly reduce out-of-pocket costs for eligible patients.

Insurance coverage for weight loss medications is inconsistent. Medications prescribed for diabetes (Ozempic, Mounjaro) tend to have better coverage because diabetes is a well-established medical condition with clear treatment guidelines.

Medications prescribed specifically for weight loss (Wegovy, Zepbound) are frequently excluded from formularies or require prior authorization. Even when covered, copays can be substantial.

The FDA has recognized obesity as a chronic disease, but insurance policy hasn't fully caught up. Check with your specific plan before assuming coverage.

Compounded versions of semaglutide and tirzepatide are available through many telehealth providers at significantly lower prices - often $200 to $500 per month including provider consultations and shipping. These are custom-made by licensed compounding pharmacies (503A or 503B) using the same active ingredients.

While compounded medications are legal and regulated, they are not FDA-approved in the same way as brand-name drugs. Reputable providers use only licensed pharmacies that follow strict manufacturing standards.

This is currently the most common path to affordable GLP-1 treatment.

The cheapest option isn't always the best value. A provider that costs slightly more but includes thorough medical oversight, responsive support, and quality medications from a reputable pharmacy may save you money in the long run by ensuring safe, effective treatment.

Start by comparing top providers on our platform - we break down pricing, medical support, and medication options side by side. You can also take our matching quiz to find a provider that fits both your needs and budget.

Brand-name Mounjaro costs approximately $1,000-$1,100/month. Zepbound (the weight-loss version) is similarly priced.

Compounded tirzepatide through telehealth providers typically runs $300-$500/month. While more expensive than compounded semaglutide, tirzepatide produces greater average weight loss - so the cost-per-pound-lost may actually be comparable.

Compare providers on our tirzepatide comparison page.