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GLP-1 Price Index & Weight Loss Statistics (September 2026)
The dated, citable record of what 9US telehealth providers publish for compounded semaglutide and tirzepatide - every price verified against the provider’s own site, every change logged - paired with the published clinical-trial results for GLP-1 weight-loss medications (STEP, SURMOUNT, SCALE).
Prices verified September 21, 2026 · 4 logged changes this month
Treatments Hub original data
What compounded GLP-1 actually costs: a 9-provider price survey
We track published prices across 9 US telehealth providers. As of September 2026, compounded semaglutide ranged from $49 to $199 per month and compounded tirzepatide from $89 to $299 per month - a fraction of the brand-name list prices for the same active ingredients, which run into four figures (below). Every figure is a price the provider publishes, verified by our team - not an estimate.
Brand medication
Active ingredient
Brand list price
Compounded from
Ozempic
Semaglutide
$1,149-$1,399/mo
$49/mo
Zepbound
Tirzepatide
$1,249-$1,599/mo
$89/mo
Wegovy
Semaglutide
$1,579-$1,799/mo
$49/mo
Source: Treatments Hub GLP-1 price index, 9 providers, verified published prices as of September 2026. Brand list prices are manufacturer/pharmacy list prices; insurance and manufacturer coupons can lower them. See the full provider-by-provider table on our cheapest GLP-1 comparison.
The GLP-1 price index: all 9 providers, verified September 21, 2026
Each row records the headline monthly price and the condition attached to it - a promotional rate, a plan length, a prepaid term. A price is never listed without its condition. Sorted by semaglutide price, cheapest first.
Compounded medications are prepared by state-licensed pharmacies and are not FDA-approved brand products. Every provider listed requires a licensed-clinician review before prescribing. Prices are cash-pay; confirm current terms on each provider’s site.
Price change log
Every time a verification pass changes a listing, the change is recorded here with the date, what we listed before, and what we list now. Newest first.
September 21, 2026
altRx
Promotional $89/month semaglutide and $149/month tirzepatide rates extended: provider now lists the sale as ending September 25 (previously September 20). Prices unchanged.
September 15, 2026
trimrx
Compounded semaglutide now listed at $149/month, the same price at every dose ($140 discount applied). Previously listed as $179 for the first month and $299 regular thereafter. Tirzepatide unchanged at $259/month.
September 14, 2026
altRx
Promotional $89/month semaglutide and $149/month tirzepatide rates confirmed; provider lists the sale as ending September 20. Regular rates remain $199 and $299.
September 14, 2026
wellmedr
Compounded semaglutide now listed at $49/month on the 12-month plan (previously listed $59) and tirzepatide at $89/month (previously $99). Same price at every dose.
Our top 2 picks
Our two recommended GLP-1 providers, shown with the same verified pricing and ratings as our full comparison.
embody offers doctor-prescribed GLP-1 weight loss treatment - compounded semaglutide and tirzepatide injections - through a 100% online process. Getting started takes a roughly 5-minute health qualifier, after which a medical practitioner reviews your chart (embody says usually within 24 hours, often under 5). Pricing is flat and simple: $69/month for semaglutide and $119/month for tirzepatide, with no insurance required, no hidden fees, and no clinic visits. Medication ships in 1-2 days in temperature-controlled, tracked, insured packaging, and embody is LegitScript-certified and works with US-based 503A compounding pharmacies. On Trustpilot, embody averages 3.8 across 8,398 reviews - an honest, mixed-to-positive record whose recent reviews cluster around two themes: responsive, proactive customer service ('from my very first inquiry I've had excellent communication... customer service updated me every step,' writes one tirzepatide patient) and the no-surprises pricing ('Love the fact that there are no surprises as in costly up front cost'). A 3.7 also means a minority of customers had negative experiences - worth reading both ends of the reviews before deciding, as with any provider.
altRx bills itself as "the #1 most affordable GLP-1 program," and its published prices largely back that up: compounded GLP-1 (semaglutide) from $89/month and GLP-1 + GIP (tirzepatide) from $149/month - flat at every dose, so the price doesn't climb as you titrate up - alongside one of the few genuine brand-name shelves in this space (Ozempic $1,149, Zepbound $1,249, Wegovy $1,579 per month). It's a self-pay telehealth service: you complete a short assessment, a licensed provider (physician, PA, or nurse practitioner) reviews it, and if appropriate a prescription goes to a licensed US pharmacy, with free shipping in about 5-7 days. No insurance is required, Buy Now, Pay Later is available, and you can pause or cancel anytime. Two things to know before the details: shipping is slower than the 1-2 day providers (embody, DirectMeds), and Trustpilot does not currently display an aggregate score on altRx's profile - the individual reviews we quote on this page are real, but there's no independent average to lean on the way there is for rivals like Medvi (4.3 across 14,836) or embody (3.8 across 8,398). One of the real 4-star reviews we surface notes a refill 'yet to be fulfilled with zero reason as to why' - worth factoring in alongside the price advantage.
Source: Pivotal published trials - STEP 1 (Wilding et al., New England Journal of Medicine, 2021) for semaglutide 2.4mg; SURMOUNT-1 (Jastreboff et al., NEJM, 2022) for tirzepatide 15mg; SCALE (Pi-Sunyer et al., NEJM, 2015) for liraglutide 3mg; SUSTAIN program for semaglutide 2mg. Figures are trial averages; individual results vary.
Most Common Side Effects
Side Effect
Semaglutide
Tirzepatide
Nausea
~40-44%
~25-33%
Diarrhea
~30%
~19-23%
Vomiting
~24%
~8-13%
Constipation
~23%
~12-17%
Source: FDA prescribing information and pivotal-trial safety data (STEP and SURMOUNT programs). Rates are approximate; side effects typically improve over time and with dose stabilization.
Weight Loss Timeline
Timeframe
What to Expect
Week 1-2
Reduced appetite, early satiety, possible mild nausea
Month 1
3-5 lbs weight loss (starting dose)
Month 2-3
~3-6% body weight loss as the dose increases
Month 6
10-15% body weight loss (semaglutide) or 15-20% (tirzepatide)
Month 12-16
Maximum results: 15% (semaglutide) to 22.5% (tirzepatide)
Source: Clinical trial averages. Individual results vary based on medication, dose, diet, and exercise.
Who Qualifies for GLP-1 Treatment?
According to FDA-approved prescribing criteria, GLP-1 weight loss medications are indicated for adults with:
BMI ≥ 30 (obesity)
BMI ≥ 27 with at least one weight-related condition (type 2 diabetes, hypertension, high cholesterol, sleep apnea)
Who should not take them
Semaglutide and tirzepatide carry an FDA boxed warning for thyroid C-cell tumors and are contraindicated for anyone with a personal or family history of medullary thyroid carcinoma or MEN 2 syndrome. They are also used with caution in people with a history of pancreatitis or gallbladder disease, and are not for use in pregnancy. Always review your full history with a licensed clinician.
Among the most effective prescription weight-loss options: in STEP 1, semaglutide 2.4 mg produced about 15% mean weight loss versus roughly 2.4% in the lifestyle-only (placebo) arm - a substantially larger effect than older weight-loss drugs.
Once-weekly injection: Both semaglutide and tirzepatide are administered as once-weekly subcutaneous injections.
Gradual dose escalation: Treatment starts at a low dose and increases monthly over 16-20 weeks to minimize side effects.
Available online: Licensed telehealth providers can prescribe GLP-1 medications through fully online medical evaluations, with home delivery in most US states.
Weight regain risk: The STEP 1 trial extension showed approximately two-thirds of weight lost was regained within one year of stopping semaglutide, supporting the case for ongoing treatment.
Dual-agonist advantage: Tirzepatide targets both GLP-1 and GIP receptors, which may explain its superior weight loss results compared to semaglutide.
Methodology & citation
Pricing: our price survey tracks the prices 9US telehealth providers publish for compounded semaglutide and tirzepatide. Every figure is a published provider price verified by our team against the provider’s own site - we do not estimate, model or extrapolate prices. The index was last verified on September 21, 2026, and every change to a listing is recorded in the change log above with its date.
Clinical data:weight-loss and safety figures are drawn from the medications’ pivotal published trials (STEP, SURMOUNT, SCALE, SUSTAIN) and FDA prescribing information, and are trial averages rather than guarantees of individual results.
Citing this page?Please attribute to “Treatments Hub GLP-1 Price Index (2026)” and link to this page. For the full provider-by-provider pricing table, see our cheapest GLP-1 comparison. This page is general information, not medical advice.
More GLP-1 guides
The rest of our weight-loss medication guides, kept to the same verified-price standard.
