The quick answerThe price that matters is the one you keep paying, not month 1. At verified prices, year one of compounded semaglutide runs from $588 on wellmedr's 12-month plan to roughly $1,800-$2,400 at month-to-month providers; tirzepatide about $500-$1,200 more. The month-2 jump comes from promos with no published end date, 20%-off-month-one offers, and memberships billed next to the drug - all visible before you pay.Prices verified on each provider’s site as of September 21, 2026.
Why is the first-month price the wrong number?
Ask a hundred people what their GLP-1 costs and most will quote the number from the sign-up page. That number is right for one month.
The price that decides whether you can stay on treatment is the one you pay in month 4, month 9 and month 12, at the dose your clinician settles you on - and across the providers we track it is sometimes the same as month 1, sometimes double. Three pricing shapes produce the gap.
An introductory price that ends after the first month or two. A membership or subscription fee billed next to the medication, so the drug price you saw was never the whole bill.
And a prepaid bundle that charges the year up front and renews. None of these is hidden, exactly; they are just not the number in the headline.
This page puts the number in the headline. Every price below is the provider's own published figure as verified in our price index, and every change we have logged is in the price-change feed.
Our top 2 picks
Our two recommended GLP-1 providers, shown with the same verified pricing and ratings as our full comparison.
Our Most Popular
1
Exceptional
9.8out of 10
Limited Offer - GLP-1 for $69/mon
Money-back guaranteeFree expedited delivery
Treatments offered
Compounded semaglutide injections (GLP-1) · Compounded tirzepatide injections (GLP-1 + GIP) · 100% online doctor review and prescription · Dosage adjustments through the patient portal
Starting price
$79$69/month
*Compounded medications are not FDA-approved.
- Compounded semaglutide ($69/mo) and tirzepatide ($119/mo)
- 5-minute health qualifier; doctor review usually within 24 hrs
- Free 1-2 day shipping - temperature-controlled, tracked, insured
- No insurance required, no clinic visits, cancel anytime
Pricing starts at
from $69/month
embody offers doctor-prescribed GLP-1 weight loss treatment - compounded semaglutide and tirzepatide injections - through a 100% online process. Getting started takes a roughly 5-minute health qualifier, after which a medical practitioner reviews your chart (embody says usually within 24 hours, often under 5). Pricing is flat and simple: $69/month for semaglutide and $119/month for tirzepatide, with no insurance required, no hidden fees, and no clinic visits. Medication ships in 1-2 days in temperature-controlled, tracked, insured packaging, and embody is LegitScript-certified and works with US-based 503A compounding pharmacies. On Trustpilot, embody averages 3.8 across 8,398 reviews - an honest, mixed-to-positive record whose recent reviews cluster around two themes: responsive, proactive customer service ('from my very first inquiry I've had excellent communication... customer service updated me every step,' writes one tirzepatide patient) and the no-surprises pricing ('Love the fact that there are no surprises as in costly up front cost'). A 3.7 also means a minority of customers had negative experiences - worth reading both ends of the reviews before deciding, as with any provider.
Read full embody review2
Exceptional
9.7out of 10
Most Comprehensive GLP-1 Medication Access
Transparent pricingNo insurance required
Treatments offered
Compounded semaglutide (GLP-1) injection · Compounded tirzepatide (GLP-1 + GIP) injection · Brand-name Zepbound and Wegovy · One simple injection per week
Starting price
$199$89/month
*Compounded medications are not FDA-approved.
- Compounded GLP-1 from $89/mo, GLP-1 + GIP from $149/mo
- Brand-name options too: Zepbound and Wegovy
- Clinician-guided - physician, PA, or nurse practitioner
- Free shipping (about 5-7 days)
Pricing starts at
from $89/month
altRx bills itself as "the #1 most affordable GLP-1 program," and its published prices largely back that up: compounded GLP-1 (semaglutide) from $89/month and GLP-1 + GIP (tirzepatide) from $149/month - flat at every dose, so the price doesn't climb as you titrate up - alongside one of the few genuine brand-name shelves in this space (Ozempic $1,149, Zepbound $1,249, Wegovy $1,579 per month). It's a self-pay telehealth service: you complete a short assessment, a licensed provider (physician, PA, or nurse practitioner) reviews it, and if appropriate a prescription goes to a licensed US pharmacy, with free shipping in about 5-7 days. No insurance is required, Buy Now, Pay Later is available, and you can pause or cancel anytime. Two things to know before the details: shipping is slower than the 1-2 day providers (embody, DirectMeds), and Trustpilot does not currently display an aggregate score on altRx's profile - the individual reviews we quote on this page are real, but there's no independent average to lean on the way there is for rivals like Medvi (4.3 across 14,836) or embody (3.8 across 8,398). One of the real 4-star reviews we surface notes a refill 'yet to be fulfilled with zero reason as to why' - worth factoring in alongside the price advantage.
Read full altRx reviewWhat do you really pay for compounded semaglutide: month 1, maintenance and year one?
Sorted by year one, lowest first. "What you keep paying" is the price the provider publishes for every month after the first, at every dose. Where a provider lists a promotional price next to a struck regular price, we show both, because the page we verified doesn't say when the promotion ends.
| Provider | Month 1 | What you keep paying | Year one | Commitment |
|---|---|---|---|---|
| wellmedr | $49 | $49 | $588 | 12-month plan for the lowest rate; cancel or change anytime |
| embody | $69 | $69 while the promo holds; $79 regular | $828 - $948 | None - month to month, cancel anytime |
| altRx | $89 | $89 while the promo holds; $199 regular | $1,068 - $2,388 | None - pause or cancel anytime; Buy Now, Pay Later |
| Medvi | $99 | $99 while the promo holds; $199 regular | $1,188 - $2,388 | None - no membership or hidden fees; HSA/FSA |
| HealthRx | $1,188 up front | $99 averaged (prepaid) | $1,188 | 12-month prepaid plan |
| DirectMeds | $147 | $147 | $1,764 | None - no membership, cancel anytime |
| trimrx | $149 | $149 | $1,788 | None - month to month |
| SHED | $159.20 | $199 | $2,348.20 - $2,388 | None - HSA/FSA approved |
| Sprout | $149 | not published | - | See provider site for plan terms |
Compounded semaglutide, providers' own published prices as verified on September 21, 2026. Year one is a range where a promotional price has no published end date: the low end assumes it holds all year, the high end is the regular price.
Two rows deserve a sentence each. wellmedr's $49 is the floor of the market, and it is a 12-month plan: the price is locked for the year, which is the point, and the plan terms are the thing to read before you sign. HealthRx's $99 is an average: the plan is $1,188 charged at checkout for twelve months, so month 1 costs the whole year, and nothing comes back if you stop in month 5. The month-to-month rows - embody, altRx, DirectMeds, trimrx - are the ones where month 4 genuinely costs what month 1 did.What do you really pay for compounded tirzepatide?
Same method, same sort. Tirzepatide costs more at every provider; the shape of each provider's pricing is the same as its semaglutide row.
| Provider | Month 1 | What you keep paying | Year one | Commitment |
|---|---|---|---|---|
| wellmedr | $89 | $89 | $1,068 | 12-month plan for the lowest rate; cancel or change anytime |
| embody | $119 | $119 while the promo holds; $129 regular | $1,428 - $1,548 | None - month to month, cancel anytime |
| DirectMeds | $147 | $147 | $1,764 | None - no membership, cancel anytime |
| altRx | $149 | $149 while the promo holds; $299 regular | $1,788 - $3,588 | None - pause or cancel anytime; Buy Now, Pay Later |
| Medvi | $166 | $166 while the promo holds; $299 regular | $1,992 - $3,588 | None - no membership or hidden fees; HSA/FSA |
| trimrx | $259 | $259 | $3,108 | None - month to month |
| SHED | $239.20 | $299 | $3,528.20 - $3,588 | None - HSA/FSA approved |
| HealthRx | $179 | not published | - | 12-month prepaid plan |
| Sprout | $199 | not published | - | See provider site for plan terms |
Compounded tirzepatide, providers' own published prices as verified on September 21, 2026. Year one is a range where a promotional price has no published end date: the low end assumes it holds all year, the high end is the regular price.
If you are choosing between the two molecules, tirzepatide vs semaglutide covers the trial results; this page only covers the money. The cheapest tirzepatide year at a verified published price is wellmedr's $1,068 on its 12-month plan; the cheapest with no commitment is embody at $1,428 if its $119 sale price holds all year, $1,548 at the regular $129.Shop GLP-1 plans by product
Every provider's published plans - cheapest first, conditions under each price.
Where does the month-2 price jump come from?
Reading the two tables, the jump shows up in exactly three places. Promotional prices with no published end date: altRx and Medvi both list a struck regular price roughly double the current one. altRx has extended its promotion repeatedly - our change log records two extensions in September alone - but "extended so far" is not "permanent", so budget for the regular price and treat the promo months as savings. Month-one discounts: SHED's 20% off applies to the first month only, and the table shows the $159.20-to-$199 step. Membership models: the providers in this index bill one all-in price, but brand-name routes often don't. ro, for example, sells the Zepbound KwikPen from $299 for the first month, then $399-449, plus a separate Body membership of $39 the first month and $74-$149 after - two line items that both step up after month 1. The full brand-name picture is in what Zepbound costs online.
The test before you pay is simple: find the sentence that says what month 2 costs. If the page doesn't have one, ask support and keep the reply.
What To Know Before Starting GLP-1 Treatment
Before starting GLP-1 treatment, it's important to understand a few key things. These medications require a prescription from a licensed clinician and aren't suitable for everyone. Some people may experience side effects, especially during the first few weeks as the body adjusts.
GLP-1s also tend to work best when combined with basic lifestyle habits like balanced nutrition and regular physical activity.
That's why choosing a provider that offers proper medical screening and ongoing follow-up support is essential for both safety and long-term success.
Are prepaid GLP-1 plans worth it?
Prepaying buys the lowest per-month figure in the table and removes the month-2 question entirely - the price can't change because you already paid it. What it adds is a different risk: the money is gone whether or not the shipments arrive, and whether or not the medication suits you.
Captured reviews across providers describe both the good version (a locked price that stayed locked) and the bad one (a plan that renewed without notice, or shipments that stopped while the charges didn't). Before any prepaid or 12-month plan, read the five questions to ask before you prepay, which quotes the reviews.
Our general rule: pay monthly for the first two or three cycles, see whether the provider ships on time and answers when you write, then decide whether a longer plan is worth the discount.
How to use these numbers
Pick your drug, find the row whose year one fits your budget, then check two things the price can't tell you: whether the provider ships on time - the shipping-times page compares each provider's published promise against what reviewers report - and whether someone answers when something goes wrong, which the provider-support comparison measures from the same captured reviews. Our cheapest GLP-1 ranking and 12-point provider checklist cover the rest. All of these treatments require a prescription from a licensed clinician, who decides whether and what to prescribe; this page is about cost, not medical suitability.